Drug Standards
Selleck Chemical LLC Salinomycin
Salinomycin traditionally used as an anti-coccidial drug has recently been shown to possess anti-cancer and anti-cancer stem cell (CSC) effects
Selleck Chemical LLC Verubecestat (MK-8931) 5mg 1286770-55-5
Verubecestat (MK-8931) is a potent and selective beta-secretase (also known as Beta-site APP-cleaving enzyme 1) inhibitor. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC A-1331852 5mg 1430844-80-6
A-1331852 is a potent and selectiveBCL-XL inhibitor with Ki value less than 0.01 nM for BCL-XL and 6 nM, 4 nM, 142 nM for Bcl-2, Bcl-W, MCL-1 respectively. It may be useful in the treatment of cancer, immune and autoimmune diseases. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC Elacridar (GF120918) 50mg 143664-11-3 GW120918
Elacridar (GF120918, GW120918) is a potent P-gp (MDR-1) and BCRP inhibitor. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
eMolecules AstaTech / BROMFENAC / 0.25g / 453190036 / 26391 / 95.000 / 91714-94-2 / MFCD00864341 / 334.169 / C15H12BrNO3
AstaTech / BROMFENAC / 0.25g / 453190036 / 26391 / 95.000 / 91714-94-2 / MFCD00864341 / 334.169 / C15H12BrNO3
Selleck Chemical LLC Methotrexate 10mM/1mL 59-05-2 NCI-C04671
Methotrexate (MTX, NCI-C04671), analog of folic acid, is a nonspecific inhibitor of the dihydrofolate reductase(DHFR) of bacteria and cancerous cells as well as normal cells. It forms an inactive ternary complex with DHFR and NADPH. Methotrexate (MTX) induces apoptosis. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medchemexpress LLC (+)-Ketoconazole | 142128-59-4 | C26H28Cl2N4O4 | 5 MG
(+)-Ketoconazole is an imidazole anti-fungal agent and a CYP3A4 inhibitor. It has been associated with androgen deficiency features in men treated for chronic mycotic infections and also acts as a cytochrome P450 inhibitor. It has been studied for its potential to affect the antischistosomal properties of quinolines against *Schistosoma mansoni* infection.
- Targets fungal and cytochrome P450 pathways
- Inhibits anti-infection and metabolic enzymes
- Soluble in DMSO (33.33 mg/mL) and various in vivo solvents (≥ 2.5 mg/mL)
- Clinical indications: candida infection, dermatophytosis, folliculitis
- Potential toxicity: teratogenesis, liver injuries, adrenal gland problems
- For research use only
Medchemexpress LLC Zileuton sodium | 118569-21-4 | 98.6% | 258.27 g/mol | C11H11N2NaO2S | 5 MG
Zileuton sodium is the sodium salt of zileuton, a potent and selective inhibitor of 5-lipoxygenase used as a research reagent to modulate leukotriene-mediated inflammatory pathways. It is supplied as a solid, high-purity chemical intended for in vitro and in vivo experimental use; not for human or therapeutic use.
- Potent, selective 5-lipoxygenase inhibitor
- Sodium salt form for improved solubility
- High purity (98.6%) suitable for research applications
- Molecular weight 258.27 g/mol; formula C11H11N2NaO2S
- Stable when stored sealed, away from moisture
- Provided in small research quantities appropriate for preclinical studies
Sigma Aldrich Fine Chemicals Biosciences Metformin Related Compound B United States Pharmacopeia (USP) Reference Standard | 1674-62-0 | 25MG
Metformin Related Compound B United States Pharmacopeia (USP) Reference Standard | Mol Wt: 151.6 | 1674-62-0 | 25MG
Cayman Chemical RacecadotrIl-d5 10mg
An internal standard for the quantification of racecadotril by GC- or LC-MS
Medchemexpress LLC Enzalutamide (Standard) | 915087-33-1 | 99.98% | C21H16F4N4O2S | 100 MG
Enzalutamide (Standard) is the analytical standard of Enzalutamide, intended for research and analytical applications. It functions as an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells and is also an autophagy activator. The compound serves as a reference standard supplied for assays and is commonly utilized in qualitative, quantitative, and methodological research experiments involving techniques such as HPLC, GC, and MS.
- For research and analytical applications
- Androgen receptor (AR) antagonist
- Autophagy activator
- Analytical standard
- Reference standard for assays
- Utilized in qualitative, quantitative, and methodological research experiments
Apexbio Technology LLC Haloperidol hydrochloride 1511-16-6 10mM (in 1mL DMSO)
Haloperidol hydrochloride is a small-molecule antagonist targeting dopamine D2 receptors It is designed to modulate dopaminergic neurotransmission thereby regulating neural pathways implicated in psychosis Haloperidol hydrochloride exerts its biological activity primarily through inverse agonist and antagonist effects on dopamine D2 receptors particularly within the mesocortical limbic and nigrostriatal pathways Based on these pharmacological properties haloperidol hydrochloride holds research potential in studying dopamine receptor functions dopamine-mediated neural circuits and the pathophysiological mechanisms underlying psychiatric disorders